Carnosine is a life extension superstar for its versatility and potency. In particular, it combats glycation, free radical damage, replicative senescence, telomere shortening and is a chelator of heavy metals. In addition, it has been found to extend the lifespan in mice by 20%.
CARNOSINE
Glycation and Oxidation
Carnosine has been known for some time now to be very effective in guarding against glycation, the insidious and devastating process over time by which tissues, particularly those of the nervous system, are irreversibly damaged by their permanent combination with sugar molecules. There are a large number of studies at this point, both in vivo and in vitro, demonstrating its efficacy as an anti-glycating agent on a wide array of different tissues and cell types including those of the nervous system and lens of the eye.1,2 In addition to protecting proteins from glycation, it also protects them from oxidation.3 In particular, it has the ability to neutralize the most destructive of protein-oxidizing free radicals – the hydroxyl radical. It was declared by one study to be the only anti-oxidant capable of protecting DNA from oxidation,4 and is key in the body’s ability to repair and remove proteins already damaged by glycation or oxidation.
Protects the eye...
...and the nervous system from glycation.
Protects DNA from oxidation.
Replicative Senescence and Telomere Shortening
As the body’s cells divide telomeres shorten, and due to the telomere position effect, the new cells are ‘older’ or more dysfunctional on a number of fronts. Eventually they become ‘senescent’ where they radically change shape, stop dividing and wait for death. These cells represent the final stage of degradation due to telomere-mediated cellular aging. We believe telomere shortening is the one true underlying cause of aging in all species, so anything that may slow down this process is invaluable to us. And Carnosine has recently been shown to both slow telomere shortening5 and independently, to delay and even revert6 replicative senescence.7
Can delay and even revert replicative senesence..
Slows telomere shortening.
In Vivo Life Extension
One study tested the effect of carnosine on life span and indicators of aging in senescence-accelerated mice. Carnosine extended the life span of the treated mice by 20% on average although the maximum lifespan was not altered.8
Warnings
Non recommandé pour les femmes en ceinte ou femmes qui allaitent. Tenir hors de portée des enfants. Conserver dans un endroit frais et sec.
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Product Code:
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TRLC002
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Package Quantity:
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60 capsules
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Shipping Weight:
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2.0000 lbs
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Serving Size:
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1 capsule
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