Chronic administration of ALCAR increased cholinergic synaptic transmission and consequently enhanced learning capacity as a cognitive function in aging rats.
S. Ando 2001
Significant improvement of several aspects of mental performance in elderly patients was found during and after Acetyl-L-Carnitine treatment.
Salvioli, G. 1994
ALCAR (Acetyl-L-Carnitine) treatment slowed down the age-related nerve cell loss in some rat brain areas.
Napoleone, P. 1990
The long-term treatment with Acetyl-L-Carnitine was found to produce positive structural changes in aging rat brains.
Ramacci, M. 1988
Feeding old rats Acetyl-L-Carnitine and Alpha Lipoic Acid significantly reduced the number of severely damaged mitochondria and increased the number of intact mitochondria in the hippocampus.
Ramacci, M. 1988
Dogs treated with Acetyl-L-carnitine exhibited significantly lower neurological deficit scores and more normal cerebral cortex lactate/pyruvate ratios than did vehicle-treated control animals.
Rosenthal, R. 1992
Acetyl-L-Carnitine showed signs of neuroprotective activity in vitro
Forloni, G. 1993
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