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Back Resveratrol - 300 mg, 30 capsules

Resveratrol and SIRT1: News in Brief

Resveratrol is a phytoalexin produced naturally by varias plants in response to stress, injury, fungal infections and UV radiation. It is found in the skin of red grapes, raspberries, blackberries, plums, peanuts, blueberries and the roots and stems of Japanese Knotweed, a native medicinal plant from China and Japan, from which we get our extract. Resveratrol is receiving a lot of attention lately for its ability to prolong life. In every species studied so far, Resveratrol has been shown to extend life expectancy.

Why Buy Resveratrol From Terraternal?
 
1

Our product passes through the MOST RIGOROUS TESTING of any resveratrol capsule in the world.

Most companies do not submit their products for independent 3rd party testing and share the Certificates of Analyis of their recent batches like we do.

But because an HPLC test is only as good as the reference standard that the sample is compared against, our Resveratrol is also tested using NMR, a sophisticated technique that directly measures the precise structural configuration of the Resveratrol molecule. Here you can see the NMR Results and Analysis of our most recent batch (R90). Terraternal is the only place in the world where you will find these strict standards for quality in Resveratrol testing.

 
2

We offer the HIGHEST PURITY of any Resveratrol product in the world.

The powder in our high purity capsules is OVER 99% Resveratrol. In both our high and medium purity capsules, 100% of the Resveratrol they contain is TRANS-RESVERATROL, as you can see in our Certificate of Analysis. (high) (medium)

This is the effective form of Resveratrol, as opposed to cis-Resveratrol, a form often carried by our competitors.

 
3

We offer the LOWEST COST PER GRAM OF ANY TRANS RESVERATROL PRODUCT on the market.

Our 500mg, 60 capsules product offers pure Trans-Resveratrol at a price of $2.40/gram. 4

At Terraternal you can make Resveratrol part of your Recurring Order, and do so along with your other anti-aging supplements. What's more, each supplement can occur with a different frequency so you don't have to hassle with reordering ever again.

5 Our capsules are 100% light-resistant, which means the Resveratrol stays in tact on our shelves and yours and are 100% Vegetarian and Kosher and Halal certified.

Resveratrol Increases Healthy Lifespan in Animals

Scientists first noticed that feeding Resveratrol to yeast lengthened their lives by 70%. As they moved up the food chain in their experiments, they find a recurring theme: Resveratrol extends lifespan.1


In November 2006, a long awaited study headed by David Sinclair and released by Harvard Medical School published the results on mice. The average lifespan of the mice were increased by 30%. And this is despite the fact that resveratrol consumption began in mid-life.Overfed mice were studied in particular, and equally surpising was the fact that Resveratrol virtually eliminated the majority of other illnesses unique to the obese mouse control group.


Caloric Restriction and SIRT1 Activation

Caloric Restriction - severe limitation of food intake - has long been known to dramatically increase the lifespan of every animal we've tried it on. It can push lifespan out by up to 55% in mice2:


Even mice beginning CR late in life, like these winners of the Methuselah Mouse Rejuvenation award:

have their lives extended by up to 35%.

Sinclair has shown that a gene called Sirt1 is turned on by a CR diet, and that it is also turned on by Resveratrol.  No other molecule is known to have this ability. Sinclair has demonstrated in rats that when the Sirt1 gene is activated, lifespan is increased, but CR does not increase it any further.  Conversely, knocking out the Sirt1 gene eliminated any beneficial effect of CR. The evidence is very convincing at this point that Resveratrol may be CR in a pill.

Age-Related Health Effects of Resveratrol

Mice on CR do not just live longer, but are healthier for longer. They are all but immune to a wide variety of diseases that most young animals (and people) are less prone to be troubled by. And this seems to be exactly the result of studies of mice that have been made with Resveratrol. For example, in the now-famous Sinclair study, the livers of the mice were autopsied and they found that the high-calorie fed mice on Resveratrol had livers compatible with those on a far healtheir diet4


Just imagine how well your body can function with Resveratrol and a healthy diet.

Resveratrol Dosage, Bioavailability and Safety

To match the dosage pound per pound of the mice in the Harvard 2006 study, one should take 500mg for each 50 lbs of one's weight per day.  That would put the dosage in the range of 1500-2500 mg per day depending on your weight.  We do not recommend at this time that children, pregnant or lactating women take the supplement.

Recently Sinclair has moved on from mice to humans, with a daily dosage of 2500mg to 5000mg of a synthetic version of Resveratrol that he claims is more bioavailable.  He has completed phase 1a safety trials using this formulation, and although waiting 50-100 years for the effects of lifespan is is not in the cards, he is testing for the specific positive health benefits seen typically seen in CR and in the 2006 mouse study.


A Toast

So here's a toast, as the tradition goes: To health, and long life!

Other Ingredients

water, hidroxy, propyl, methyl, cellulose.

Money Back Guarantee

If for any reason you are unsatisfied with a Terraternal product, simply return the unused portion to us within 30 days for a full refund. No questions asked.

Product Code: TR2020
Package Quantity: 30 capsules
Shipping Weight: 2.4000 lbs
Serving Size: 1 capsule
 

Resveratrol Supplement Facts


 Supplement Amount Per Serving % Daily Value
 Trans-resveratrol 300 mg †
 From 303 mg Polygonum Cuspidatum extract  
 † Daily Value not established  
   

References
  • 1:
    Fish (60%): Valenzano et al.: Resveratrol Prolongs Lifespan and Retards the Onset of Age-Related Markers in a Short-Lived Vertebrate. Current Biology 16, 296-300, February 7, 2006.
    Yeast (70%): Yeast: Howitz KT et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 2003 Sep 11; 425:191-6.
    Fly, Roundworm (Drosophila melanogaster and Caenorhabditis elegans) Bass T et al. Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans. Mechanisms of Ageing and Development 128: 546-52
  • 2: Graph adapted from: Weindruch R, et al. (1986). "The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake." Journal of Nutrition, April, 116(4), pages 641-54.
  • 3: Baur JA, Sinclair DA. Therapeutic potential of resveratrol: the in vivo evidence. Nature Rev Drug Disc 2006 Jun;5(6):493-506
  • 4: Sinclail et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature Nov 2006, 337-342.
    See also: http://web.med.harvard.edu/sites/RELEASES/html/11_1Sinclair.html