Resveratrol and Sirt1: News In Brief
Resveratrol is phytolalexin produced naturally by several plants in response to
stress, injury, fungal infection and UV radiation. It is found in the skins
of red grapes, rasberries, mulberries, plums, peanuts, blueberries and the roots
and stalks of Japanese Knotweed, a traditional Chinese and Japanese medicinal plant,
from which we get our extract.
Resveratrol is gaining a lot of attention lately as a life extension supplement.
In every species studied so far, Resveratrol has been shown to extend its lifespan.
Why Buy Resveratrol From Terraternal?
Our product passes through the MOST RIGOROUS TESTING
of any resveratrol capsule in the world.
Most companies do not submit their products for independent 3rd party testing and
share the Certificates of Analyis of their recent batches
like we do.
But because an HPLC test is only as good as the reference standard that the sample
is compared against, our Resveratrol is also tested using
NMR, a sophisticated technique that directly measures the precise structural
configuration of the Resveratrol molecule. Here you can see the NMR Results and Analysis of one of our recent batches. Terraternal
is the only place in the world where you will find these strict standards for quality
in Resveratrol testing.
We offer the HIGHEST PURITY of any Resveratrol
product in the world.
The powder in our high purity capsules is OVER 99% Resveratrol. In both our
high and medium purity capsules, 100% of the Resveratrol they contain is TRANS-RESVERATROL,
as you can see in our Certificate of Analysis. (high) (medium)
This is the effective form of Resveratrol, as opposed to cis-Resveratrol, a form
often carried by our competitors.
We offer the LOWEST COST PER GRAM OF ANY TRANS
RESVERATROL PRODUCT on the market.
Our 500mg, 60 capsules product offers pure Trans-Resveratrol at a price of
At Terraternal you can make Resveratrol part of your
Recurring Order, and do so along with your other anti-aging supplements.
What's more, each supplement can occur with a different frequency so you don't have
to hassle with reordering ever again.
Our capsules are 100% light-resistant
which means the Resveratrol stays in tact on our shelves and yours and are 100%
Vegetarian and Kosher and Halal certified.
Resveratrol Dosage, Bioavailability and Safety
To match the dosage pound per pound of the mice in the Harvard 2006 study, one should
take 500mg for each 50 lbs of one's weight per day.
That would put the dosage in the range of 1500-2500 mg per day depending on your
weight. We do not recommend at this time that children, pregnant or lactating
women take the supplement.
Recently Sinclair has moved on from mice to humans, with a daily dosage of 2500mg
to 5000mg of a synthetic version of Resveratrol that he claims is more bioavailable.
He has completed phase 1a safety trials using this formulation,
and although waiting 50-100 years for the effects of lifespan is is not in the cards,
he is testing for the specific positive health benefits seen typically seen in CR
and in the 2006 mouse study.
Resveratrol Increases Healthy Lifespan in Animals
Scientists first noticed that feeding Resveratrol to yeast lengthened their lives
by 70%. As they moved up the food chain in their experiments, they find a recurring
theme: Resveratrol extends lifespan.1
In November 2006, a long awaited study headed by David Sinclair and released by Harvard Medical
School published the results on mice. The average lifespan of the mice were increased
by 30%. And this is despite the fact that resveratrol consumption began in mid-life.Overfed
mice were studied in particular, and equally surpising was the fact that Resveratrol
virtually eliminated the majority of other illnesses unique to the obese mouse
Caloric Restriction and SIRT1 Activation
- severe limitation of food intake - has long been known to dramatically increase
the lifespan of every animal we've tried it on. It can push lifespan out by up to
55% in mice2:
Even mice beginning CR late in life, like these winners of the Methuselah Mouse Rejuvenation award:
have their lives extended by up to 35%.
has shown that a gene called Sirt1 is turned on by a CR diet, and that it
also turned on by Resveratrol. No other molecule is known to have
this ability. Sinclair has demonstrated in rats that when the Sirt1 gene is activated,
lifespan is increased,
but CR does not increase it any further. Conversely, knocking out the Sirt1 gene eliminated any beneficial effect of CR. The evidence is very convincing at this point that Resveratrol may be CR in a pill.
Age-Related Health Effects of Resveratrol
Mice on CR do not just live longer, but are healthier for longer.
They are all but immune to a wide variety of diseases that most young animals (and
people) are less prone to be troubled by. And this seems to be exactly the result
of studies of mice that have been made with Resveratrol. For example, in the now-famous
Sinclair study, the livers of the mice were autopsied and they found that the high-calorie
fed mice on Resveratrol had livers compatible with those on a far healtheir diet4
Just imagine how well your body can function with Resveratrol and a healthy
So here's a toast, as the tradition goes: To health, and long life!
Money Back Guarantee
If for any reason you are unsatisfied with a Terraternal product, simply return the unused portion to us within 30 days for a full refund. No questions asked.