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Alpha Lipoic Acid
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Anti-Oxidant
ALA (Alpha Lipoic Acid) reversed I/R-induced oxidant responses and improved microscopic damage and renal function in wistar albino rats.
Sehirli, O. 2008
Early administration of Lipoic Acid provided protective effects against endotoxin-induced oxidative stress in the lungs and supported the idea that alpha-lipoic acid is a free radical scavenger and a potent antioxidant.
Goraca, A. 2008
Alpha-LA had a beneficial effect on diabetes-induced cystopathy in a rat by ameliorating oxidative stress and normalizing the NGF level in the bladder.
Jiang, Y. 2008
Treatment of 12-month-old SAMP8 mice with LA reversed all three indexes of oxidative stress.
Farr, S. 2003
Long Term Safety
The long term (2 year) treatment of rats with Alpha Lipoic Acid appeared to result in no adverse effects.
Cremer, D. 2006
Anti Aging
Mortality was slightly lower in rats treated with Alpha Lipoic Acid than in controls.
Cremer, D. 2006
Gylcation
Alpha lipoic acid is suggested to posses a dual lipid lowering and anti-atherosclerotic properties.
Amom, Z. 2008
LA was shown protective against sulfite-induced visual evoked potentials alterations and oxidative stress in the brain and retina.
Derin, N. 2008
Alpha Lipoic Acid may also posses a lipid lowering effect indicated with low plasma TCHOL and LDL levels and reduced the athero-lesion formation in rabbits fed a high cholesterol diet.
Zulkhairi, A. 2007
Administration of Alpha Lipoic Acid had a positive influence on tail tendon collagen glycation and other variables in high-fructose-fed rats.
Thirunavukkarasu, V. 2005
Alpha-lipoic acid had beneficial effects on the development of diabetic retinopathy via inhibition of accumulation of oxidatively modified DNA and nitrotyrosine in the retina.
Kowluru, R. 2004
Other
Alpha Lipoic Acid effectively managed systemic inflammation in inflammation-induced mice.
Jesudason, E. 2008
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